The Yale Precipitating Events Project (PEP) is a cohort study based in New Haven CT that enrolled individuals aged 70 years or older. Its methods have been published elsewhere [15, 16]. Briefly, 754 community dwelling, English speaking, non-disabled persons with life expectancy and plans to stay in the area for more than 12 months were enrolled in the study. Comprehensive home-based assessments were completed at baseline and every 18 months. The 18-month assessment included 681 participants aged 72 to 98 years. This report uses the baseline and 18 month follow up data to contrast with each other and to compare the properties of the new indexes created in this data set with previously reported frailty indexes. At baseline, most participants (n = 487, 64.6%) were women, and most (n = 682, 90.5%) were white, with a mean Mini-Mental State Examination (MMSE) [17] score of 26.8 (SD = 2.50). Mortality was checked monthly for nine years from the baseline interview and was confirmed by obituaries and death certificates.
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Survival analyses were done using bi-variate and multivariate Cox Regression analyses with the frailty index as the independent variable and age and gender as covariates on each of the two survey waves. The survival calculations were based on the available nine year mortality data from the baseline survey. The 18 month follow up survival calculations based from the available seven and a half year (from 18 month interview) mortality data. 2ff7e9595c
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